ABSTRACT
In Brazil, little is known about the maintenance of results after treatment of cognitive-behavioral therapy (CBT) for major depressive disorder (MDD). The objective of this study was to verify the effectiveness of individual psychotherapeutic treatment from CBT for depressive symptoms within 6 and 12 months after the intervention. We evaluated 94 participants with MDD from the Beck Depression Inventory (BDI-II). There was significant posttreatment response (p < 0.001), with no difference between the end of the treatment and the symptom assessment at 6 (p = 0.486) and 12 months (p = 0.098). A significant positive correlation was observed between the intensity of depressive symptoms at the baseline and the reduction of initial symptoms for 12-month follow-up (r = 0.49; p < 0.001). CBT significantly reduces depressive symptoms by maintaining this condition up to 12 months post-intervention without significant influence of other characteristics beyond the intensity of depressive symptoms at the beginning of the therapeutic process.
No Brasil, pouco se sabe sobre a manutenção dos resultados pós-tratamento da terapia cognitivo-comportamental (TCC) para o transtorno depressivo maior (TDM). Objetivou-se verificar a efetividade do tratamento psicoterápico individual a partir da TCC para os sintomas depressivos em um período de 6 e 12 meses pós-intervenção. Avaliaram-se 94 participantes com TDM a partir do Inventário Beck de Depressão (BDI-II). Houve resposta significativa pós-tratamento (p < 0,001), não ocorrendo diferenças entre o final do tratamento e a avaliação dos sintomas aos 6 (p = 0,486) e 12 meses (p = 0,098). Uma correlação positiva significativa foi observada entre a intensidade dos sintomas depressivos no baseline e a redução de sintomas iniciais para o acompanhamento de 12 meses (r = 0,49; p < 0,001). A TCC reduz significativamente os sintomas depressivos mantendo essa condição até 12 meses pós-intervenção sem influência significativa de outras características além da intensidade dos sintomas depressivos no início do processo terapêutico.
Este estudio verificó la efectividad del tratamiento psicoterápico individual a partir de la terapia cognitiva conductual (TCC) para los síntomas depresivos dentro de los 6 y 12 meses post-intervención. Se evaluaron 94 participantes con TDM a partir del Inventario Beck de depresión (BDI-II). Se observó una respuesta significativa post-tratamiento (p < 0,001), no ocurrieron diferencias entre el final del tratamiento y la evaluación de los síntomas a los 6 (p = 0,486) y 12 meses (p = 0,098). Había una correlación positiva significativa entre la intensidad de los síntomas depresivos en el baseline y la reducción de los síntomas iniciales para el seguimiento de 12 meses (r = 0,49; p < 0,001). La TCC reduce significativamente los síntomas depresivos manteniendo esa condición hasta 12 meses después de la intervención sin influencia significativa de otras características además de la intensidad de los síntomas depresivos al inicio del proceso terapéutico.
Subject(s)
Humans , Male , Female , Treatment Adherence and ComplianceABSTRACT
Objective: To evaluate the prevalence of alcohol abuse and/or dependence in a population-based sample of young adults and assess the prevalence of comorbid mood disorders, anxiety, and suicide risk in this population. Methods: This cross-sectional, population-based study enrolled 1,953 young adults aged 18-35 years. The CAGE questionnaire was used to screen for alcohol abuse and/or dependence, with CAGE scores ≥ 2 considered positive. Psychiatric disorders were investigated through the structured Mini International Neuropsychiatric Interview (MINI). Results: Alcohol abuse and/or dependence was identified in 187 (9.60%) individuals (5.10% among women and 15.20% among men). Alcohol abuse and/or dependence were more prevalent among men than women, as well as among those who used tobacco, illicit drugs or presented with anxiety disorder, mood disorder, and suicide risk. Conclusion: These findings suggest that alcohol abuse and/or dependence are consistently associated with a higher prevalence of psychiatric comorbidities, could be considered important predictors of other psychiatric disorders, and deserve greater public heath attention, pointing to the need for alcohol abuse prevention programs.
Subject(s)
Humans , Male , Female , Adolescent , Adult , Young Adult , Anxiety/epidemiology , Anxiety Disorders/epidemiology , Suicide, Attempted/statistics & numerical data , Mood Disorders/epidemiology , Alcoholism/epidemiology , Anxiety/complications , Socioeconomic Factors , Brazil/epidemiology , Illicit Drugs , Comorbidity , Prevalence , Cross-Sectional Studies , Surveys and Questionnaires , Risk Factors , Alcoholism/psychologyABSTRACT
Objective: To investigate peripheral levels of interleukin-10 (IL-10) in patients with major depressive disorder (MDD) and bipolar disorder (BD) and evaluate the relationship between IL-10, age of disease onset, and duration of illness. Methods: Case-control study nested in a population-based cohort of 231 individuals (age 18-24 years) living in Pelotas, state of Rio Grande do Sul, Brazil. Participants were screened for psychopathology using the Mini-International Neuropsychiatric Interview (MINI) and the Structured Clinical Interview for DSM-IV (SCID-I). Serum IL-10 was measured using commercially available immunoassay kits. Results: Peripheral levels of IL-10 were not significantly different in individuals with MDD or BD as compared to controls. However, higher IL-10 levels were found in MDD patients with a later disease onset as compared with controls or early-onset patients. In addition, IL-10 levels correlated negatively with illness duration in the MDD group. In the BD group, age of onset and duration of illness did not correlate with IL-10 levels. Conclusion: Higher levels of IL-10 are correlated with late onset of MDD symptoms. Moreover, levels of this cytokine might decrease with disease progression, suggesting that an anti-inflammatory balance may be involved in the onset of depressive symptoms and disease progression in susceptible individuals.
Subject(s)
Adolescent , Adult , Female , Humans , Male , Young Adult , Bipolar Disorder/blood , Depressive Disorder, Major/blood , /blood , Age Factors , Age of Onset , Analysis of Variance , Biomarkers/blood , Bipolar Disorder/pathology , Bipolar Disorder/psychology , Case-Control Studies , Depressive Disorder, Major/pathology , Depressive Disorder, Major/psychology , Disease Progression , Psychiatric Status Rating Scales , Socioeconomic Factors , Time FactorsABSTRACT
Anastrepha pseudanomala Norrbom was reared in fruits of Couma utilis (Apocynaceae), and also collected in McPhail traps in Ferreira Gomes county, State of Amapá, Brazil.
Subject(s)
Animals , Apocynaceae/parasitology , Tephritidae , BrazilABSTRACT
Anastrepha anomala Stone was obtained from Parahancornia amapa (Huber) Ducke (Apocynaceae) fruits, and Anastrepha hastata Stone from Cheiloclinium cognatum (Miers.) (Hippocrateaceae) in the State of Amapá, Brazil. Two braconids, Doryctobracon sp. and Opius bellus Gahan, were reared from the latter fruit fly species. This is the first record of P. amapa as a fruit fly host. C. cognatum is the first host known to A. hastata. Both braconids are also the first records of parasitoids for this species.
Anastrepha anomala Stone foi obtida de frutos de Parahancornia amapa (Huber) Ducke (Apocynaceae) e Anastrepha hastata Stone de Cheiloclinium cognatum (Miers.) (Hippocrateaceae) no Amapá, sendo obtidos dois braconídeos, Doryctobracon sp. e Opius bellus Gahan, dessa espécie. Este é o primeiro registro de P. amapa como hospedeiro de moscas-das-frutas. C. cognatum é o primeiro hospedeiro conhecido de A. hastata e os braconídeos são também os primeiros registros de parasitóides dessa espécie.
Subject(s)
Animals , Female , Male , Hymenoptera , Tephritidae , Brazil , Hymenoptera/growth & development , Tephritidae/growth & developmentABSTRACT
The external morphological characters of the egg and five instars of Phthia picta (Drury) are described and illustrated.
Neste trabalho é apresentada a descrição dos caracteres morfológicos externos do ovo e dos cinco ínstares ninfais de Phthia picta (Drury), incluindo ilustrações.